Article: A clinical review of montelukast in the treatment of seasonal allergic rhinitis

Abstract

Seasonal allergic rhinitis is a disease characterized by sneezing, nasal congestion, rhinorrhea, and itching, conventionally treated with intranasal corticosteroids and anti-histamines. The leukotriene receptor antagonist montelukast (Singulair, Merck) recently gained FDA approval for the treatment of seasonal allergic rhinitis. This review will evaluate published literature comparing the efficacy of montelukast to current therapeutic seasonal allergic rhinitis options. Articles were identified through searches of MEDLINE, EMBASE, and PreMEDLINE between 1990 and week 8 of 2003. While studies have shown the efficacy of montelukast in the treatment of seasonal allergic rhinitis, ...

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