Article: High-pressurized orange juice consumption affects plasma vitamin C, antioxidative status and inflammatory markers in healthy humans1

Manuscript received 5 March 2003. Initial review completed 1 April 2003. Revision accepted 21 April 2003.

ABSTRACT We examined the bioavailability of vitamin C in orange juice processed using high pressure (HP) and its effects on plasma levels of vitamin C, uric acid (UA), F2-isoprostanes (8-epiPGF^sub 2[alpha]^), C-reactive protein (CRP) and prostaglandin E^sub 2^ (PGE^sub 2^) in a healthy human population. Subjects (6 men, 6 women) enrolled in the study consumed 500 mL/d of HP orange juice for 14 d, corresponding to an intake of 250 mg of vitamin C. On d 1 of the study, subjects drank the juice in one dose; on d 2 until the end of the study, d 14, they drank 250 mL in the morning and 250 ...

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