Article: Aromatic amino acids are utilized and protein synthesis is stimulated during amino acid infusion in the ovine fetus

ABSTRACT The purpose of this study was to determine whether the ovine fetus is capable of increased disposal of an amino acid load; if so, would it respond by increased protein synthesis, amino acid catabolism or both? A further purpose of the study was to determine whether the pathways of aromatic amino acid catabolism are functional in the fetus. Late gestation ovine fetuses of well-nourished ewes received an infusion of Aminosyn PF alone (APF), and Aminosyn PF + glycyl-L-tyrosine (APF+GT) at rates estimated to double the intake of these amino acids. The initial study, using APF, was performed at 126 +/- 1.4d;the APF+GT study was performed at 126 _ 1.4 d; the APF+GT study was performed at ...

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