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Article: Lutein interacts with ascorbic acid more frequently than with [alpha]-tocopherol to alter biomarkers of oxidative stress in female Zucker obese rats1,2
- Article from:
- The Journal of Nutrition
- Article date:
- September 1, 2003
- Author:
CopyrightCopyright American Institute of Nutrition Sep 2003. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT The influence of dietary lutein, with and without moderate amounts of vitamin C (VC) or vitamin E (VE), on biomarkers of oxidative stress was examined in rats. Nine groups of immature Zucker obese (fa/fa) and lean female rats (8/group) consumed ad libitum for 8 wk the AIN-93G diet (Control) to which was added either dl-[alpha]-tocopherol acetate (VE) at 0.60 mg/kg or ascorbic acid (VC) at 0.75 mg/kg diet. Each of these diets contained lutein oil (FloraGlo) at 0.5 (Lut0.5) or 1.0 (Lut1.0) mg/kg diet. Weight gain, food efficiency and relative liver weight were higher in obese than in lean rats. Although liver malondialdehyde (MDA) concentrations were significantly higher in obese ...