Article: (Beta-carotene), carotenoids and the prevention of coronary heart disease

Beta-Carotene, Carotenoids and the Prevention of Coronary Heart Disease1

ABSTRACT The importance of low density lipoprotein (LDL) oxidation to the atherosclerotic process has led to the examination of Beta-carotene as a possible preventive agent. Several epidemiologic studies show an inverse association between serum/adipose Beta-carotene levels and coronary heart disease risk. Randomized clinical trials, however, have not shown any benefit, and perhaps even an adverse effect, of Beta-carotene supplementation. A number of possible confounding factors may explain the inconsistency between the trials and epidemiologic evidence. Other carotenoids that are correlated with Beta-carotene both in ...

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