Article: Use of Conjugated Linoleic Acid (CLA) Enrichments to Examine the Effects of trans-8, cis-10 CLA, and cis-11, trans-13 CLA on Milk-Fat Synthesis*

Abstract

Conjugated linoleic acid (CLA) supplements have typically been comprised of 4 isomers (trans-8, cis-10; cis-9, trans-11; trans-10, cis-12; and cis-11, trans-I3 CLA). Abomasal infusion of pure isomers has shown that trans-W, cis-12 CLA is a potent inhibitor of milk-fat synthesis, whereas cis-9, trans-11 CLA has no effect. However, there appear to be additional fatty acids that inhibit milk-fat synthesis, and the objective of this study was to investigate the effects of additional CLA isomers present in CLA supplements. Four rumen fistulated Holstein cows (141 ± 8 DIM, mean ± SE) were randomly assigned in a 4 × 4 Latin square experiment. Treatments were abomasal infusion of (1) ...

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