Article: Dietary Soy Protein Improves Body Composition and Lipids but Not Insulin Sensitivity in Obese, Male Cynomolgus Monkeys

We previously showed that dietary soy protein improves body composition, lipids, and insulin sensitivity in ovariectomized cynomolgus monkeys. Human studies suggest that there may be gender-specific responses to soy protein and soy isoflavones, so we wanted to examine the effect of soy protein on body composition, lipids, and insulin sensitivity in obese, insulin-resistant male monkeys. The study design was a Latin-square, with each monkey (n = 8) receiving each of the following dietary proteins for 10 wk: 1) casein and lactalbumin, 2) soy(+), and 3) alcohol-washed soy(-). The following measures were assessed at the end of each treatment phase: food consumption, body weight, body ...

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