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PREMATURE OVARIAN FAILURE AS AN AUTOIMMUNE DISEASE

PS55

Since 1967 definition of Premature Ovarian Failure is "the unphysiological cessation of menses before the age of 40 y.o."The frequency in near 1%.

Ovaries during different period of life from prepuberal, postpubcral o during reproductive stage can be the target of many diverse autoantigen which clinical feature of this disease is the Premature Ovarian Failure(POF) or Infertility. Failure of Ovarian Function may be present isolated or associated with other/s autoimmune pathologies, especially with adrenal autoimmune failure, or hypothyroidism, IDDM due to D Islet Autoantibody, Parathyroid Type 1 and Type 2 Autoimmune Polyglandular Syndrome are described, which include 2 or more ...

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