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Article: A Clinicopathologic Evaluation of Follicular Lymphoma Grade 3A Versus Grade 3B Reveals No Survival Differences

Article from:
Archives of Pathology & Laboratory Medicine
Article date:
August 1, 2004
Author:
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* Context.-The World Health Organization classification recommends categorizing grade 3 follicular lymphomas based on the presence of centrocytes (grade 3A) or of sheets of centroblasts (grade 3B). The clinical significance of this practice is not known.

Objective.-To determine whether grade 3 follicular lymphoma subtype is associated with prognosis.

Design.-Multi-institutional retrospective case series.

Main Outcome Measure.-Overall survival.

Results.-Forty-five cases of grade 3 follicular lymphoma without diffuse large B-cell lymphoma were studied (35 cases of grade 3A, 10 cases of grade 3B) from 21 men and 24 women (median age, 67 years; mean age, 63.8 years; range, 26-86 years). ...

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