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Effect of Enteral Nutrition of Monoacetoacetin on Bacterial Translocation in Burned Rats
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JPEN, Journal of Parenteral and Enteral Nutrition
- Article date:
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September 1, 2004
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Copyright informationCopyright American Society for Parenteral and Enteral Nutrition Sep/Oct 2004. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT. Background: Bacterial translocation (BT) occurs under stress, and enteral nutrition is said to be effective in counteracting this effect. The usefulness of IV nutrition of monoacetoacetine (MA) under stress has been reported previously, and we studied the effect of enteral nutrition of MA as it is related to BT. Methods: Rats were given 13.6% MA or 15% glucose (Glu) via gastrostomy, and after 4 days a 30% full-thickness burn was made. Before and after administration of the burn, we measured serum cytokines; amounts of bacteria in the mesenteric lymph node (MLN), liver, and spleen (estimation of BT); mucosal thickness of the terminal ileum; and body weight changes. To confirm the ...
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