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Article: N(alpha)-(1-deoxy-D-fructos-1-yl)-L-arginine, an antioxidant compound identified in aged garlic extract
- Article from:
- The Journal of Nutrition
- Article date:
- March 1, 2001
- Author:
CopyrightCopyright American Institute of Nutrition Mar 2001. Provided by ProQuest LLC. (Hide copyright information)
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Nalpha-(1-Deoxy-D-fructos-1-yl)-L-Arginine, an Antioxidant Compound Identified in Aged Garlic Extract1
ABSTRACT Aged garlic extract (AGE) has been shown to have antioxidant activity. The organosulfur compounds, S-allyl-L-cysteine and S-allylmercapto-L-Cysteine, are responsible, at least in part, for the antioxidant activity of AGE. To identify major active components, we fractionated AGE, using hydrogen peroxide scavenging activity as an antioxidative index. Strong activity in the amino acid fraction was found and the major active compound was identified as Na-(I-deoXy-D-fructos-1-yi)-L-arginine (Fru-Arg). Antioxidant activity of Fru-Arg was comparable to that of ascorbic acid, scavenging ...