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Evidence of a Novel Cell Signaling Role for Extracellular Adenosine Triphosphates and Diphosphates in Arabidopsis

Extracellular ATP is a known receptor agonist in animals and was previously shown to alter plant growth, and so we investigated whether ATP derivatives could function outside plant cells as signaling agents. Signaling responses induced by exogenous nucleotides in animal cells typically include in creases in free cytoplasmic calcium concentration ([Ca^sup 2+^]^sub cyt^). We have evaluated the ability of exogenously applied adenosine 5'-[γ-thio]triphosphate (ATPγS), adenosine 5'-[β-thio]diphosphate (ADPβS), and adenosine 5'-O-thiomonophosphate to alter [Ca^sup 2+^]^sub cyt^ in intact apoaequorin transgenic Arabidopsis thaliana seedlings. ATPγS and ADPβS increase ...

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