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Article: Anticancer Activities of White Button Mushrooms
- Article from:
- The Journal of Nutrition
- Article date:
- December 1, 2004
- Author:
CopyrightCopyright American Institute of Nutrition Dec 2004. Provided by ProQuest LLC. (Hide copyright information)
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Mushrooms
Anticancer Activities of White Button Mushrooms. Shiuan Chen. Department of Surgical Research, Beckman Research Institute of the City of Hope, Duarte, CA.
Research from our laboratory has demonstrated that white button mushrooms contain phytochemicals that can suppress 2 enzymes, aromatase and steroid 5-α-reductase. Aromatase converts androgen to estrogen. It is commonly known that estrogen promotes the development of breast cancer, especially in postmenopausal women. Aromatase inhibitors that suppress the formation of estrogen are currently being used in the treatment of estrogen-dependent breast cancer. Steroid 5-α-reductase converts testosterone to dihydrotestosterone ...