Article: Effect of Five Cysteine-Containing Compounds on Three Lipogenic Enzymes in Balb/cA Mice Consuming a High Saturated Fat Diet

ABSTRACT: The in vivo effects of N-acetyl cysteine (NAC), S-allyl cysteine, S-ethyl cysteine (SEC), S-methyl cysteine (SMC), and S-propyl cysteine (SPC) against hyperlipidemia development and oxidation stress in Balb/cA mice consuming a high saturated fat diet were examined. The influence of these agents on plasma levels of glucose, insulin, uric acid, TG, cholesterol, and the activity of three lipogenic enzymes-glucose-6-phosphate dehydrogenase, malic enzyme, and FA synthase-was determined. All mice consumed the coconut oil-basd, high saturated fat diet, water, and cysteine or one of the five cysteine-containing compounds for 4 wk. The diet with 18% saturated fat significantly elevated the ...

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