Article: Cystic Fibrosis: Everything You Need to Know

Cystic Fibrosis: Everything You Need to Know Edited by Wayne Kepron; New York: Firefly Books, 2004; ISBN 1-55297-7 40-4; 190 pages

Cystic fibrosis is the most common autosomal recessive disorder in Caucasian people. Approximately one in 25 Caucasians is a heterozygous carrier for this disorder, with one newborn in every 2,500 live births being affected. The disorder is caused by a genetic mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene located on the long arm of chromosome 7. Cystic fibrosis is the major cause of severe chronic lung disease and exocrine pancreatic insufficiency in children. The disorder causes significant morbidity and mortality both in ...

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