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Article: ^sup 68^Ga-Labeled Peptides in Tumor Imaging

Article from:
The Journal of Nuclear Medicine
Article date:
January 1, 2005
Author:
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Radiolabeled peptides are of increasing interest in nuclear oncology. Special emphasis has been given to the development of peptides labeled with positron emitters. Among these, ^sup 68^Ga deserves special attention, because it is available from an in-house generator rendering ^sup 68^Ga radiopharmacy independent of an onsite cyclotron. ^sup 68^Ga has a half-life of 68 min and decays by 89% through positron emission. The parent, ^sup 68^Ge, is accelerator produced and decays with a half-life of 270.8 d by electron capture. Currently, at least 1 commercial and several in-house generators are available. ^sup 68^Ge is strongly absorbed on metal oxides or organic material, making a ^sup ...

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