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Article: Clinical Hypnosis Modulates Functional Magnetic Resonance Imaging Signal Intensities and Pain Perception in a Thermal Stimulation Paradigm
- Article from:
- Regional Anesthesia and Pain Medicine
- Article date:
- November 1, 2004
- Author:
CopyrightCopyright Churchill Livingstone Inc., Medical Publishers Nov/Dec 2004. Provided by ProQuest LLC. (Hide copyright information)
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Objective: This study was designed to describe regional changes in blood oxygenation level dependent signals in functional magnetic resonance images (fMRI) elicited by thermal pain in hypnotized subjects. These signals approximately identify the neural correlates of the applied stimulation to identify neuroanatomic structures involved in the putative effects of clinical hypnosis on pain perception.
Methods: After determination of the heat pain threshold of 12 healthy volunteers, fMRI scans were performed at 1.5 Tesla by using echoplanar imaging technique during repeated painful heat stimuli. Activation of brain regions in response to thermal pain during hypnosis (using a fixation and ...