Magazine article from our research archive:

Spinal 2-Chloroprocaine: Minimum Effective Dose

Background and Objectives: Recent studies using preservative-free 2-chloroprocaine (2-CP) for spinal anesthesia have shown it to be a reliable short-acting agent in the 30-mg to 60-mg range. Investigations of doses below this range have not been performed.

Methods: To establish the minimum effective dose for spinal anesthesia, this randomized, double-blind, crossover study investigates the characteristics of spinal 2-CP 10 mg and 20 mg in 8 volunteers and compares the results with previous data obtained for 30 to 60 mg in the same human model.

Results: Peak block height, regression to L1, tolerance to tourniquet, and transcutaneous electrical stimulation all increased with increasing doses ...

Related newspaper, magazine, and journal articles:

See all results. Or, try our Advanced Search.

Newsweek Harper's Magazine The Washington Post Chicago Tribune Crain's Chicago Business PRNewswire Pediatric News The Nation Advertising Age The Economist (US) A FREE trial gives you access to over 60 million articles! Access over 3,500 publications with a FREE trial!