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Article: Dietary Fatty Acids and Cholesterol Differentially Modulate HDL Cholesterol Metabolism in Golden-Syrian Hamsters1,2
- Article from:
- The Journal of Nutrition
- Article date:
- March 1, 2005
- Author:
CopyrightCopyright American Institute of Nutrition Mar 2005. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT
Dietary fatty acids alter HDL cholesterol concentrations, presumably through mechanisms related to reverse cholesterol transport. The effect of dietary fats (coconut oil, butter, traditional stick margarine, soybean oil, canola oil) differing in fatty acid profile on this antiatherogenic process was assessed with respect to plasma lipids; exogenous and endogenous lecithin-cholesterol acyltransferase (LCAT), cholesterol ester transfer protein (CETP), phospholipid transfer protein (PLTP) activities; and LCAT, apolipoprotein (apo) A-I and scavenger receptor B class-1 (SR-B1) mRNA abundance. Golden-Syrian hamsters were fed a nonpurified (6.25 g/100 g fat) diet containing an additional ...