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Article: Proline-Rich Proteins Moderate the Inhibitory Effect of Tea on Iron Absorption in Rats
- Article from:
- The Journal of Nutrition
- Article date:
- March 1, 2005
- Author:
CopyrightCopyright American Institute of Nutrition Mar 2005. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT
Tea inhibits iron absorption in studies in which tea is given with radiolabeled iron to humans as a single dose. Our objective was to test the hypothesis that proline-rich proteins (PRPs) may act as a defense against this effect by forming complexes with tannins, thereby preventing them from inhibiting iron absorption. Two studies were conducted. In study 1, rats were given test solutions containing ^sup 59^FeCl^sub 3^ in water, tea, or tea + gelatin (T/G). In study 2, the rats were divided into 3 groups and assigned to one of 3 nutritionally complete diets: control, tea (5 g tea tannin/kg diet), or T/G (5 g tea tannin + 60 g gelatin/kg diet). Rats were fed the respective diets for ...