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Article: Plasma Zinc Concentrations Are Depressed during the Acute Phase Response in Children with Falciparum Malaria1
- Article from:
- The Journal of Nutrition
- Article date:
- April 1, 2005
- Author:
CopyrightCopyright American Institute of Nutrition Apr 2005. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT
Plasma concentrations of some micronutrients are altered in the setting of acute infectious or inflammatory stress. Previous studies have provided conflicting evidence concerning the extent and direction of changes in plasma zinc concentrations during the acute phase response. We carried out an observational cohort study in 689 children enrolled in a randomized trial of zinc supplementation during acute falciparum malaria in order to evaluate the relation between plasma zinc concentration and the acute phase response. Plasma zinc was measured by atomic absorption spectrophotometry. On admission, 70% of all subjects had low plasma zinc (<9.2 µmol/L). Multivariate analysis of ...
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