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Short-Term Very Low Calory Diet Reduces Oxidative Stress in Obese Type 2 Diabetic Patients

Summary

Oxidative stress is higher in obese diabetic than in non-diabetic subjects. This pilot study evaluates oxidative stress during short-term administration of a very low calory diet in obese persons. Nine obese Type 2 diabetic patients (age 55±5 years, BMI 35.9±1.9 kg/m^sup 2^) and nine obese non-diabetic control subjects (age 52±6 years, BMI 37.3±2.1 kg/m^sup 2^) were treated by a very low calory diet (600 kcal daily) during 8 days stay in the hospital. Serum cholesterol, triglycerides, non-esterified fatty acids (NEFA), beta-hydroxybutyrate (B-HB), ascorbic acid (AA), alpha-tocopherol (AT), plasma malondialdehyde (MDA) and superoxide dismutase (SOD) activity in erythrocytes were ...

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