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Effect of Recombinant Human Growth Hormone and Enteral Nutrition on Short Bowel Syndrome

ABSTRACT. Background: Studies showed that bowel rehabilitation therapy, including recombinant human growth hormone (rhGH), nutrition support, glutamine, and dietary fiber, promotes intestinal adaptation in patients with short bowel syndrome. The aim of the current study was to determine if enteral nutrition and rhGH are effective in weaning short bowel patients off total parenteral nutrition (TPN). Methods: Thirty-seven patients with short bowel syndrome received bowel rehabilitation therapy for 4 weeks. Thirtyfour patients were treated within 2 years after short bowel syndrome. Treatment included nutrition support from enteral nutrition 500 to 1500 kcal/d, oral glutamine 0.6 g/kg/d, plus a ...

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