Articles > Health magazines > Medical magazines > Regional Anesthesia and Pain Medicine articles > July 2005

Article: Scavenging Nanoparticles: An Emerging Treatment for Local Anesthetic Toxicity

Article from:
Regional Anesthesia and Pain Medicine
Article date:
July 1, 2005
Author:
Copyright

A dreaded complication of local anesthetic use in regional anesthesia is systemic toxicity from unintentional intravascular local anesthetic injection. Although systemic toxic reactions are not common after peripheral nerve block, 7.5 to 20 events per 10, 000 in adults,1 they can be life-threatening and resistant to treatment.2-6 Recent data from an American Society of Anesthesiology Closed Claims Project demonstrate that unintentional intravenous local anesthetic injection was the second largest category of block-related regional anesthesia claims that resulted in death or brain damage.7

The manifestations of local anesthetic toxicity range from local neurotoxic and myotoxic reactions to ...

Read all of this article with a FREE trial

Related newspaper, magazine, and journal articles:

Article: Lipid Infusion Accelerates Removal of Bupivacaine ...
Regional Anesthesia and Pain Medicine;  July 1, 2006 ;     700+ words ... ... 0016). Late lipid infusion, 75 seconds after ... Cardiac toxicity, Local anesthetic, Lipid emulsion ... reversing signs of local anesthetic overdose.13-15 ... method is intravenous lipid infusion.16 Weinherg et ...

Article: Local anesthetic toxicity--does product labeling ...
Regional Anesthesia and Pain Medicine;  November 1, 2002 ;     700+ words ... ... Warnings" sections in the labeling of local anesthetic solutions. An adverse reaction is ... modifications in the labeling, the local anesthetic formulation, or both. This review ... local anesthetics. The usefulness of local anesthetic labeling in guiding regional anesthetic ...

Article: Buprenorphine added to the local anesthetic for ...
Regional Anesthesia and Pain Medicine;  July 1, 2001 ;     700+ words ... ... addition of certain opiates to the local anesthetic used for brachial block may provide ... the relative contributions of the local anesthetic and the opiate to the postoperative ... of the anesthesia provided by the local anesthetic, bupivacaine. By repeating the study ...

Article: Buprenorphine added to the local anesthetic for ...
Regional Anesthesia and Pain Medicine;  March 1, 2002 ;     700+ words ... ... Objectives: Buprenorphine added to local anesthetic solutions for supraclavicular block ... previous study when compared with local anesthetic block alone. That study, however ... to 1 of 3 groups. Group I received local anesthetic (1% mepivacaine, 0.2% tetracaine ...

Article: Does Local Anesthetic Dilution Influence the ...
Regional Anesthesia and Pain Medicine;  September 1, 2009 ;     700+ words ... ... dose, volume, and concentration of local anesthetic and the quality and success of regional ... using 3 different volumes of the same local anesthetic dose influences the success rate of ... focused on blocks using a fixed dose of local anesthetic in different volumes (and ...

Article: Local Anesthetic Myotoxicity
Regional Anesthesia and Pain Medicine;  July 1, 2004 ;     700+ words ... ... a rare and uncommon side effect of local anesthetic drugs. Intramuscular injections of ... or continuous administration. all local anesthetic agents that have been examined are ... weeks. Subcellular pathomechanisms of local anesthetic myotoxicity are still not understood ...

Article: Restricted infraclavicular distribution of the local ...
Regional Anesthesia and Pain Medicine;  January 1, 2003 ;     700+ words ... ... and Objectives: The distribution of local anesthetic after different approaches for brachial ... We compared the distribution of local anesthetic within the neurovascular space in ... the distribution of a solution of local anesthetic containing radiologic contrast medium ...

Article: Ultrasonographic guidance reduces the amount of local ...
Regional Anesthesia and Pain Medicine;  November 1, 1998 ;     700+ words ... ... in-1 blocks reduces the amount of local anesthetic compared to NS guidance. Methods ... group A). Conclusion. The amount of local anesthetic for 3-in-1 blocks can be reduced ... obturator nerve by a single injection of local anesthetic (1). Since 1973, numerous authors ...

 
 
Newsweek Harper's Magazine The Washington Post Chicago Tribune Crain's Chicago Business PRNewswire Pediatric News The Nation Advertising Age The Economist (US) A FREE trial gives you access to over 80 million articles! Access over 6,500 publications with a FREE trial!

Find articles, research, and archives