Article: A DNA fingerprinting simulation laboratory for biology students

HOW-TO-DO-IT

Hands-on experimentation To solve a mock forensic problem

Restriction fragment polymorphism (RFLP) analysis or DNA fingerprinting is a powerful technique with many applications in genetics and forensic science (Bunk 2000; Strachan & Read 1999). Basic laboratory techniques involved in RFLP analysis, such as restriction enzyme digestion of DNA and agarose gel electrophoresis, are important laboratory techniques for undergraduate biology majors to learn. These techniques can be adapted for research projects by high school and undergraduate students (Vann et al. 1998). However, the expense associated with many of the reagents involved in RFLP analysis, and hazards-such as the ...

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