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Markers of Oxidative Stress in Diabetic Mothers and Their Infants During Delivery
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Physiological Research
- Article date:
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July 1, 2005
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Copyright informationCopyright Institute of Physiology 2005. Provided by ProQuest LLC. (Hide copyright information)
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Summary
Oxidative stress is probably a pathophysiological process leading to disadvantageous outcomes in diabetic pregnancies. We aimed to map a complex of potential markers of oxidative stress in this condition. Diabetic mothers had significantly higher concentrations of thiobarbituric acid reactive substances in the plasma [TBARS] both before (p<0.0001) and after (p<0.001) delivery and also their newborns showed higher values of TBARS (p<0.0001) in comparison with the control group. Diabetic mothers also showed lower concentrations of reduced glutathione in erythrocytes [GSH] both before (p<0.05) and after (p<0.01) delivery and their infants also had lower levels of GSH ...
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