Magazine article from our research archive:
|
|
The effect of water on the rate of conformational change in protein allostery
- Article from:
-
Biophysical Journal
- Article date:
-
November 1, 2001
- Author:
-
;
;
|
Copyright informationCopyright Biophysical Society Nov 2001. Provided by ProQuest LLC. (Hide copyright information)
|
ABSTRACT The influence of solvation on the rate of quaternary structural change is investigated in human hemoglobin, an allosteric protein in which reduced water activity destabilizes the R state relative to T. Nanosecond absorption spectroscopy of the heme Soret band was used to monitor protein relaxation after photodissociation of aqueous HbCO complex under osmotic stress induced by the nonbinding cosolute poly(ethylene glycol) (PEG). Photolysis data were analyzed globally for six exponential time constants and amplitudes as a function of osmotic stress and viscosity. Increases in time constants associated with geminate rebinding, tertiary relaxation, and quaternary relaxation were ...
Related newspaper, magazine, and journal articles:
|
UC San Diego Team Determines Cellular Stress Within Body Is Critical...
Ascribe Higher Education News Service;
July 6, 2004 ;
700+ words
......particular type of cellular stress called osmotic stress is of critical importance to cell growth...cell proliferation under conditions of osmotic stress and is also necessary for the body's immune response to invading pathogens. Osmotic stress occurs when the concentration of ...
|
|
Integration of wounding and osmotic stress signals determines the...
Plant Physiology;
July 1, 2003 ;
700+ words
......named AtM4, are rapidly induced by osmotic stress or abscisic acid (ABA) treatment. Reporter...untranslated region is essential for the osmotic stress and wounding induced expression of...signals derived from both wounding and osmotic stress. Abscisic acid (ABA) is the major plant...
|
|
Cyclic AMP and Aquaporin Trafficking
Plant Physiology;
August 1, 2004 ;
397 words
......target membrane under conditions of osmotic stress. Indeed, in animals, regulatory...distribution of McTIPl;2 is altered by osmotic stress. Differences in the response of McTIPl;2 to salt and osmotic stress suggest that the ionic component...
|
|
Identification of a Novel Gene Family Involved in Osmotic Stress Response...
Genetics;
November 1, 2006 ;
700+ words
......accumulates glycerol in response to osmotic stress, activated primarily by MAP kinase...different from yeast to mount a response to osmotic stress. ALL living organisms have mechanisms...taurine (BURG et al. 1997). Adaptation to osmotic stress has been studied extensively in yeast...
|
|
Proteomic Identification of Annexins, Calcium-Dependent Membrane Binding...
Plant Cell;
June 1, 2004 ;
700+ words
......annAt4, displayed hypersensitivity to osmotic stress and abscisic acid (ABA) during germination...and AnnAt4 play important roles in osmotic stress and ABA signaling in a Ca^sup 2+^-dependent...cytosol, which in turn induce ionic and osmotic stress in plants, respectively. ...
|
|
Osmotic stress induces terminal differentiation in cultured normal human...
In Vitro Cellular & Developmental Biology;
May 1, 2008 ;
700+ words
......possible signal is dehydration or osmotic stress. To test this hypothesis, we investigated the effects of osmotic stress on markers of differentiation...induce a dehydration effect or osmotic stress on the keratinocytes. These sorbitol...
|
|
Osmotic induction of stress-responsive gene expression in the lobster...
The Biological Bulletin;
December 1, 2002 ;
700+ words
......Homarus americanus, encounters osmotic stress throughout its life cycle. To understand the molecular basis of osmotic stress responses in vivo, we used homologous...polyubiquitin during hypo- and hyper-osmotic stress in abdominal muscle and hepatopancreas...
|
|
An Arabidopsis GSK3/shaggy-like gene that complements yeast salt...
Plant Physiology;
April 1, 1999 ;
700+ words
......suggest that AtGSK1 is involved in the osmotic stress response in Arabidopsis. Abbreviations...changes that occur upon exposure to osmotic stress (Walton, 1980; DuPont, 1992; Bohnert...of different mechanisms to cope with osmotic stress. Responses are especially well understood...
|
|
Osmotic and curvature stress affect PEG-induced fusion of lipid vesicles...
Biophysical Journal;
April 1, 2002 ;
700+ words
......close contact was not influenced by osmotic stress or membrane curvature, although pore...same part of the fusion process as osmotic stress. We interpret this result to suggest...concentrations of 20-40 wt%, causing osmotic stress of cells or vesicles when PEG added...
|
|
Novel Regulation of Aquaporins during Osmotic Stress1
Plant Physiology;
August 1, 2004 ;
700+ words
......regulation and redistribution in response to osmotic stress was investigated. Ice plant (Mesembryanthemum...maintain cellular osmolarity under osmotic-stress conditions. It seems intuitively obvious...which accompanies the perception of osmotic stress, have been shown to regulate the ...
|
|
Uncoupling the Effects of Abscisic Acid on Plant Growth and Water...
Plant Physiology;
October 1, 2004 ;
700+ words
......ABA levels increase in response to osmotic stress has been greatly assisted by knowledge...AAO3, and ABA3/LOS5, is increased by osmotic stress (Xiong et al., 2001). Furthermore...wild-type plants when challenged with osmotic stress. In a screen of T-DNA insertion-tagged...
|
|
The role of hydration on the mechanism of allosteric regulation: In situ...
Biophysical Journal;
January 1, 2003 ;
700+ words
......water-accessible surface area, isobaric osmotic stress experiments in aqueous cosolutions...agree with the ones determined by osmotic stress in aqueous cosolutions, from the linkage...Parsegian et al., 1995). The proposal of osmotic stress strategy has greatly contributed to...
|
See all results.
Or, try our
Advanced Search.
|