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Protein increases white blood cells ability to protect
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DVM
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September 1, 2005
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Copyright informationCopyright Advanstar Communications, Inc. Sep 2005. Provided by ProQuest LLC. (Hide copyright information)
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SAN DIEGO - Researchers at the University of California, San Diego have identified how white blood cells boost their fighting power against bacteria, a discovery providing useful information for potential new treatments.
A recent study, led by Randall Johnson, UCSD professor of biology and Victor Nizet, associate professor of pediatrics at the UCSD School of Medicine, shows that when exposed to disease-causing bacteria, white blood cells increase their levels of hypoxia inducible transcription factor-1, or HIF-I, a protein that causes white blood cells to release antimicrobial compounds.
Researchers found when cells are treated with chemicals that raise HIF-I levels they may have a stronger ...
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