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Intubation Conditions Following Rocuronium: Influence of Induction Agent and Priming
- Article from:
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Anaesthesia and Intensive Care
- Article date:
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August 1, 2005
- Author:
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Copyright informationCopyright Australian Society of Anaesthetists Aug 2005. Provided by ProQuest LLC. (Hide copyright information)
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SUMMARY
A small priming dose of rocuronium can shorten the onset time of neuromuscular blockade. Induction agents with less cardiovascular depression also reduce the onset time. We hypothesized that ketamine, compared to thiopentone, would reduce onset time and improve intubating conditions following priming. Sixty patients ASA I to II, randomized by computer-generated sequence to four groups were investigated in a double-blind controlled trial. In the two groups with priming, 0.04 mg/kg of rocuronium was followed by three minutes of priming interval. Induction was followed by an intubation dose of 0.4 mg/kg of rocuronium. After 30 seconds, intubation was attempted within a further 20 ...