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[beta]-Carotene Attenuates the Paradoxical Effect of Tobacco Smoke on the Mortality of Rats after Experimental Myocardial Infarction1,2
- Article from:
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The Journal of Nutrition
- Article date:
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September 1, 2005
- Author:
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Copyright informationCopyright American Institute of Nutrition Sep 2005. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT
The objective of this study was to investigate the effects of exposure to tobacco smoke (ETS) in rats that were or were not supplemented with dietary β-carotene (BC), on ventricular remodeling and survival after myocardial infarction (MI). Rats (n = 189) were allocated to 4 groups: the control group, n - 45; group BC administered 500 mg/kg diet, n = 49, BC supplemented rats; group ETS, n = 55, rats exposed to tobacco smoke; and group BC+ETS, n = 40. Wistar rats weighing 100g were administered one of the treatments until they weighed 200 to 250 g (~5 wk). The ETS rats were exposed to cigarette smoke for 30 min 4 times/d, in a chamber connected to a smoking device. After ...
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