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Article: Role of Momordica charantia in maintaining the normal levels of lipids and glucose in diabetic rats fed a high-fat and low-carbohydrate diet
- Article from:
- British Journal of Biomedical Science
- Article date:
- July 1, 2005
- Author:
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Copyright informationCopyright Step Publishing Ltd. 2005. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT
This study aims to assess whether or not a methanol extract of Momordica charantia is able to normalise lipid and glucose levels in diabetic rats fed a high-fat and a low-carbohydrate diet. Different doses of the extract are administered orally for 45 days. The rats are bled at the beginning of the experiment and at 15-day intervals. Blood glucose, triglyceride, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and cholesterol are estimated. Results showed that M. charantia extract normalised blood glucose level, reduced triglyceride and LDL levels and increased HDL level. The animals reverted to a diabetic state once the M. charantia extract was discontinued.
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