Article: Are nondipolar components of electrocardiogram correlated to repolarization abnormality in ischemic patients or to noise?

Joel Xue, PhD(a), Robert Farrell, PhD(a), Scott Wright, MD(c), Milos Kesek, MD(c,b) (a GE Healthcare, Milwaukee, WI, USA; b Mayo Clinic Foundation, Rochester, MN, USA; c Norrland University Hospital, Umea, Sweden)

Background: The nondipolar components of the T wave have been assumed to reflect a local repolarization inhomogeneity. The aim of this study is 2-fold: to find the relationship between the nondipolar components and the signal-to-noise ratio of electrocardiograms (ECGs), and also to find if they can be used as additional features for stratifying patients with chest pain in a computerized ECG interpretation algorithm.

Methods: Using principal component analysis, the ST-T segment of ...

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