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Use of rocuronium and magnesium sulphate

We read the article by Turan et al1 with great interest. However, we do not understand the need for administering the entire intubating dose of rocuronium (0.6 mg/kg) before the administration of thiopentone. Rocuronium provides good intubating conditions within 60 seconds2. Had rocuronium been used in a priming dose there might have been some justification.

Turan et al reported mild pain in 10% of their patients on injection of magnesium sulphate. In a recent study we observed that pretreatment with magnesium sulphate itself caused pain in 31% of patients. Of these, 6% reported severe pain, 21% moderate, and 4% mild, respectively3. We are of the opinion that a drug that itself causes ...

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