Article: Dietary zinc deficiency alters 5 alpha-reduction and aromatization of testosterone and androgen and estrogen receptors in rat liver

Dietary Zinc Deficiency Alters 5alpha-Reduction and Aromatization of Testosterone and Androgen and Estrogen Receptors in Rat Liver(1)

AE-SON OM(2) AND KYUNG-WON CHUNG*(3)

* Department of Anatomical Sciences, University of Oklahoma College of Medicine, Oklahoma City, OK 73104

Zinc is an essential nutrient, one of the most abundant biological trace metals, and an indispensable element in growth and reproduction in males and females. Zinc maintains the structural integrity of DNA (Slater et al. 1971, Wu and Wu 1983) and plays an important role in the synthesis of nucleic acid and protein (Prasad and Oberleas 1973, Slater et al. 1971), nuclear binding of androgen receptors (Colvard and Wilson ...

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