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Peripheral blood CD34+ cell counts allow improved management of peripheral blood stem cell collections
- Article from:
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British Journal of Biomedical Science
- Article date:
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January 1, 2004
- Author:
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;
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Copyright informationCopyright Step Communications Ltd. 2004. Provided by ProQuest LLC. (Hide copyright information)
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The use of peripheral blood (PB) CD34+ cell counts on the day of, or the day prior to, peripheral blood stem cell harvest (PBSCH) to predict CD34+ progenitor cell yield has been the subject of considerable interest in recent years. Since 1996, we have followed the reports of those who have studied the relationship between PB CD34+ cell counts (and other indicators such as PB white blood cell count [WBC]) and the final CD34+ cell concentration following apheresis. Most reports have demonstrated a correlation between PB CD34+ cell count and harvest yield,1-9 while one has reported poor correlation.10
Between 1996 and September 2002, PB CD34+ cell counts and WBC data were collected on 80 ...
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