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Article: Creutzfeldt-Jakob disease and blood transfusions: A meta-analysis of case-control studies
- Article from:
- Military Medicine
- Article date:
- December 1, 2001
- Author:
CopyrightCopyright Association of Military Surgeons of the United States Dec 2001. Provided by ProQuest LLC. (Hide copyright information)
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A meta-analysis of five published case-control studies that examined the association between previous blood transfusions and Creutzfeld-Jakob disease was performed. The results demonstrated that controls were more likely (p < 0.001, odds ratio = 1.56, 95% confidence interval, 1.22-1.98) to have received previous blood transfusions (18.70 than Creutzfeld-- Jakob disease patients (12.9%), suggesting that selection bias of the control populations had occurred.
Introduction
Individuals who develop Creutzfeldt-,Jakob disease (CJD) do donate blood in the preclinical stage of their disease.1 The U.S. Food and Drug Administration did ban blood donations from individuals who lived in the United ...