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Article: Dietary iron levels and hypoxia independently affect iron absorption in mice
- Article from:
- The Journal of Nutrition
- Article date:
- July 1, 1996
- Author:
CopyrightCopyright American Institute of Nutrition Jul 1996. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT The effect of dietary iron levels on the hypoxic response of iron absorption was investigated by feeding mice diets of different iron composition and determining iron absorption. Eight groups of mice were fed a purified diet consisting of casein, corn oil and sucrose with vitamins and iron-free mineral supplements. Groups A-D were fed a nonpurified diet until 6 wk old and then switched to purified diet for 4 d. Groups E-H were fed purified diet for 4 wk from weaning. Groups C, D, G and H were exposed to hypoxia (53.3 kPa) for the last 3 d of the study. Groups A, C, E and G received the low iron purified diet (<1 mg iron per kg); the other groups received the same diet ...