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A preliminary investigation of genomic screening in cervical carcinoma by comparative genomic hybridization
- Article from:
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Indian Journal of Medical Research
- Article date:
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November 1, 2005
- Author:
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Copyright informationCopyright Indian Council of Medical Research Nov 2005. Provided by ProQuest LLC. (Hide copyright information)
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Background & objectives: Available clinical, radiological and histopathologic risk factors are not adequate for accurate prognosis in uterine cervix carcinoma. Hence there is a need to identify indicators to select high risk cases. Most cancers occur and progress through step-wise somatic genetic mutations. Thus screening of whole genome for specific genomic alterations and its outcome following treatment may predict prognosis. The present study was carried out to investigate genomic alterations associated with cervical carcinoma and any association of genomic alterations with clinico-pathologic parameters.
Methods: Cervical carcinoma cases (n = 4) were subjected to protocol based ...
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