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Tazarotene Gel Reduced Pitting And Onycholysis.(in fingernail psoriasis)

ANAHEIM, CALIF -- Onycholysis associated with fingernail psoriasis responded well to tazarotene 0.1% gel in a preliminary single-center study presented at the American Academy of Dermatology's Academy 2001 meeting.

Dr. Richard K. Scher and his associates at Columbia-Presbyterian Medical Center, New York, evaluated 31 adults with psoriasis affecting at least two nails. The condition had to include at least three visible characteristics, including pitting, onycholysis, subungual hyperkeratosis, leukonychia, nail plate crumbling and/or loss, splinter hemorrhages, or nail bed discoloration.

Twenty one patients were randomized to apply tazarotene gel to each affected ...

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